BioConcepts

minimal genomeMinimalgenom (ger.)

• The minimal set of genes necessary for the survival of an organism in a laboratory environment.  
  category organism

  1994

  minmal genome size required for life

  Itaya, M. (1994). Accounting for minmal genome size required for life. Nucleic Acids Sympos. Ser. 31, 231-232.

  1995

  Supposing that there is a limited number of ‘indispensable’ genetic loci for bacteria, can the least genetic material or the size of a hypothetical minimal genome be deduced?

  Itaya, M. (1995). An estimation of minimal genome size required for life. FEBS 326, 257-260: 257.

  1996

  Now, in the 1990s, the title [viz. “On being the right size”] is used to discuss efforts to define the minimal genome content necessary and sufficient for a living cell.

  Maniloff, J. (1996). The minimal cell genome “On being the right size”. Proc. Nat. Acad. Sci. U.S.A. 93, 10004-10006: 10004.

  1999

  Ethical considerations in synthesizing a minimal genome

  Cho, M.K. et al. (1999). Ethical considerations in synthesizing a minimal genome. Science 286, 2087-2090.