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genetic programgenetisches Programm (ger.)

  • A series of instructions especially as coded in the sequence of the bases in the DNA which influence or determine the expresson of phenotypic traits.
    information
    1960
    built into the genetic program, so to speak, there is a ›curtain cell‹, statistically speaking, at a definite age
    Upton, A.C. (1960). [Discussion statement]. In: Strehler, B.L. (ed.). The Biology of Aging. A Symposium Held at Gatlinburg, Tennessee, May 1-3, 1957: 62.
    1961

    [The completely individualistic and yet also species-specific controls the development of the central and peripheral nervous systems, of the sense organs, of the hormones, of physiology and morphology, is the program for the behavior computer of this individual. [...] The purposive action of an individual, insofar as it is based on the properties of its genetic code, therefore is no more or less purposive than the actions of a computer that has been programmed to respond appropriately to various inputs

    Mayr, E. (1961). Cause and effect in biology. Science 134, 1501-1506: 1504; 1505.]

    1961
    the genome contains not only a series of blue-prints, but a coordinated program of protein synthesis and the means of controlling its execution
    Jacob, F. & Monod, J. (1961). Genetic regulatory mechanisms in the synthesis of proteins. J. Molec. Biol. 3, 318-356: 354.
    1962
    a genetic program could be altered in the course of evolution by adding new processes that would modify a simpler form into a more complex one
    Simon, H.A. (1962). The architecture of complexity. Proc. Amer. Philos. Soc. 106, 467-482: 480.
    1964

    The germ plasm of a fertilized egg contains in its DNA a coded genetic program that guides the development of the young organism and its reactions to the environment

    Mayr, E. (1964). The evolution of living systems. Proc. Nat. Acad. Sci. USA 51, 934-941: 939.

    1996
    The genetic program refers to the totality of information provided by the genes, whereas a developmental program may refer only to that part of the genetic program that is controlling a particular group of cells
    Wolpert, L. (1996). Principles of Development: 21.

Peluffo, A.E. (2015). The “genetic program”: Behind the genesis of an influential metaphor. Genetics. 2015 200, 685-696.